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INTERNAL MEDICINE II AND MEDICAL THERAPY

Academic year and teacher
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Versione italiana
Academic year
2022/2023
Teacher
GIOVANNI ZULIANI
Credits
9
Didactic period
Secondo Semestre

Training objectives

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Modulo: 000351 - FARMACOLOGIA
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INTERNAL MEDICINE
To acquire diagnostic and therapeutic skill in order to be able to recognize and manage the most important internistic diseases and syndromes. Particular importance will be dedicated to the problem oriented clinical approach and to differential diagnosis procedures, with reference to gender differences. Some metabolic disease largely prevalent in Western countries will also be also discussed from the physiopathological, clinical, and therapeutic point of view.
During the course you will also try to develop the capacity to face an ethical problem which can intersect the daily clinical activity, through the acquisition of the methodology for its analysis.
PHARMACOLOGY
The course aims to provide students with the theoretical basis of drug discovery and development as well as pharmacovigilance methods. The student is also expected to acquire the diagnostic and therapeutic skills to recognize and treat the main acute and chronic non-professional intoxications.

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Modulo: 47781 - MEDICINA INTERNA
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INTERNAL MEDICINE
To acquire diagnostic and therapeutic skill in order to be able to recognize and manage the most important internistic diseases and syndromes. Particular importance will be dedicated to the problem oriented clinical approach and to differential diagnosis procedures, with reference to gender differences. Some metabolic disease largely prevalent in Western countries will also be also discussed from the physiopathological, clinical, and therapeutic point of view.
During the course you will also try to develop the capacity to face an ethical problem which can intersect the daily clinical activity, through the acquisition of the methodology for its analysis.
PHARMACOLOGY
This course is designed to increase the student's knowledge in the field of chemotherapy, explaining the mechanisms of action of antibiotics should be used and how the different classes of drugs in clinical situations. The course also highlights the proper use of antibiotics to contain and reduce resistance. The course fits chemotherapy in other disciplines, such as infectious diseases and internal medicine.

Prerequisites

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Modulo: 000351 - FARMACOLOGIA
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Good knowledge of basic human anatomy, physiology, pathology, and pharmacology
Familiarity with general and special pharmacology. Background in cellular and molecular biology.
Basic notion in ethics and critical thinking

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Modulo: 47781 - MEDICINA INTERNA
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Good knowledge of basic human anatomy, physiology, pathology, and pharmacology
Familiarity with general and special pharmacology and microbiology. Background in cellular and molecular biology.
Basic notion in ethics and critical thinking

Course programme

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Modulo: 000351 - FARMACOLOGIA
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INTERNAL MEDICINE
Presentation and discussion of the principal syndromes of internal medicine and of the principal metabolic diseases with particular focus on clinical methodology, differential diagnosis and specific treatment.
Discuss the clinical approach oriented for problems or syndromic frameworks and the clinical reasoning in the differential diagnosis, with reference to gender differences
PHARMACOLOGY
Phases of preclinical and clinical development of a drug. Principles of pharmacovigilance. Antidotal therapy. Main acute intoxications (paracetamol, acetylsalicylic acid, benzodiazepines). Addictions. Main chronic intoxications (heroin, cocaine, amphetamines, psychedelics, alcohol).

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Modulo: 47781 - MEDICINA INTERNA
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INTERNAL MEDICINE
Presentation and discussion of the principal syndromes of internal medicine and of the principal metabolic diseases with particular focus on clinical methodology, differential diagnosis and specific treatment.
Discuss the clinical approach oriented for problems or syndromic frameworks and the clinical reasoning in the differential diagnosis, with reference to gender differences
PHARMACOLOGY
General Principles of Chemotherapy. ß-lactam antibiotics, Aminoglycosides, Quinolones, Clindamycin, Glicopeptides, Macrolides. Antigungal agents. Antibiotic prophylaxis in surgery. Anticancer drugs

Didactic methods

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Modulo: 000351 - FARMACOLOGIA
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Lectures and exercises in the ward.
For discussion of ethically relevant clinical cases - Structure of a meeting:
1) 15’: Presentation of the case with ethical implication by a clinician
2) 30’: Discussion of the case by the students divided into groups
3) 15’: Presentation of the group analysis
4) 15’: Critical discussion by the teacher of the students’ presentation
5) 15’ General discussion
PHARMACOLOGY
Lectures.


------------------------------------------------------------
Modulo: 47781 - MEDICINA INTERNA
------------------------------------------------------------
Lectures and exercises in the ward.
For discussion of ethically relevant clinical cases - Structure of a meeting:
1) 15’: Presentation of the case with ethical implication by a clinician
2) 30’: Discussion of the case by the students divided into groups
3) 15’: Presentation of the group analysis
4) 15’: Critical discussion by the teacher of the students’ presentation
5) 15’ General discussion
PHARMACOLOGY
Lectures.

Learning assessment procedures

INTERNAL MEDICINE
Written exam: 60 multiple choice questions (each with 5 answers). Each answer is worth 0.5 points if correct; wrong answer or no answer 0 points. With all the correct answers you get the praise. Allotted time: 90 minutes. The lower positive votation (18/30) will be obtained with 36 exact answers. Decimal scores (0.5) will be round to the lower score. The objective of the test is to verify the ability to compare and to connect differed topics developed during the course.
PHARMACOLOGY
Written exam: 31 multiple choice questions (each with four answers). Each question is worth 1 points if correct; wrong answer or no answer 0 points. With all the correct answers you get the praise. Allotted time: 40 minutes.
Due to existing prerequisites we advise to take the written test in pharmacology before the one in internal medicine.
THE FINAL GRADE IS A WEIGHTED AVERAGE OF THE MARKS OBTAINED IN EACH TEST.

Reference texts

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Modulo: 000351 - FARMACOLOGIA
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INTERNAL MEDICINE
Harrison, Principi di Medicina Interna, Casa Ed. Ambrosiana
Rugarli, Medicina Interna sistematica, Elsevier Ed.
Papadakin, McPhee, Rabow, Current Medical Diagnosis and Treatment, Piccin editore
Harold, Medicina Interna. Compendio essenziale per la pratica clinica, Monduzzi editore
Papers suggested over the course
PHARMACOLOGY
Goodman and Gillman's, The Pharmacological Basis of Therapeutics, XII ed.

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Modulo: 47781 - MEDICINA INTERNA
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INTERNAL MEDICINE
Harrison, Principi di Medicina Interna, Casa Ed. Ambrosiana
Rugarli, Medicina Interna sistematica, Elsevier Ed.
Papadakin, McPhee, Rabow, Current Medical Diagnosis and Treatment, Piccin editore
Harold, Medicina Interna. Compendio essenziale per la pratica clinica, Monduzzi editore
Papers suggested over the course
PHARMACOLOGY
Goodman and Gillman's, The Pharmacological Basis of Therapeutics, XII ed.