BioFINE - BioFunctional IntraNeural Electrodes

biofine.jpgBioFunctional IntraNeural Electrodes : In BioFINE we will develop flexible intraneural multielectrode arrays, capable of interfacing peripheral nerves e.g. to transfer input/output signals from bionic limbs. Specifically, we address the challenge of long term tissue integration and chronic stability, by addressing three aspects of biocompatibility: 1) We develop novel fabrication methods allowing the intraneural interface to be defined at even finer resolution than before; 2) we explore functionalizations which will control the tissue response by combined surface anchored and surface eluted agents; 3) we address structural biocompatibility on a system level by engineering novel implantable interconnects which reduced tethering forces and improve prospects for high channel count interfaces. Fine-tuned bioactivity will safe-guard surrounding neural tissue in the initial stages of healing, and implants of sub-cellular dimensions and tissue compatible biomechanics, will safe-guard tissue healthy in the longer term. The combined approach will offer optimal conditions to bridge the gap from electrode to neuron and generate a long term functional peripheral nerve interface. Indeed, each of the three technological advancements would on their own have substantial impact on neurotechnology, reaching far beyond intraneural interfaces.

Notizie (in italiano)


Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Innovation Council and SMEs Executive Agency (EISMEA). Neither the European Union nor the granting authority can be held responsible for them

Project details

Scientific responsability: Stefano Carli

Funding source: HORIZON EUROPE


Start date: 1 April 2023 - end date: 31 March 2026

EU contribution: 1.945.622,00 €

EU contribution to UniFe: 469.014,00


  • Chalmers Tekniska Hogskola Ab, Sweden
  • Albert-Ludwigs-Universitaet Freiburg - Alu-Fr, Germany
  • Universita degli Studi di Ferrara, Italy
  • Universidad Autonoma de Barcelona, Spain