IONCHAN-IMMUNRESPON - Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches

The function of ion channels in immune cells is an emerging field of great basic science and clinical interest because they provide powerful molecular targets to modulate immune cell function. The Ionchan-Immunrespon network is a novel and exciting enterprise that involves internationally recognised scientists across 15 European countries. The specific aims are i) to develop a strong European workforce to understand the role of ion channels in immune cells, and how deregulation of their function can cause disease, ii) to identify new targets for therapeutic immuno-interventions through modulation of ion channels. Our unique combination of biophysical approaches combined with molecular biology, cell biology and immunology provides a powerful approach for dissecting the functional cell biology of the immune system.

The Action therefore will strengthen academic research in Immunology within Europe and foster closer collaborations with drug and diagnostics development programs in industry.

Project details

Action member: Francesco Di Virgilio

 Funding source: COST

Start date 31/03/2015 - end date 30/03/2019


  • University of Tours, France - Chair
  • Johannes Kepler University Linz, Austria
  • University of Veterinary Medicine, Austria
  • University of Liège, Belgium
  • Medical Faculty Banja Luka, Bosnia and Herzegovina
  • Institute Rudjer Boskovic, Croatia
  • Center for Systems Biology, Czech Republic
  • University of Copenhagen, Denmark
  • Rigshospitalet, Denmark
  • Protobios OÜ, Estonia
  • Institut Curie, France
  • Institut National de la Santé et la Recherche Médicale, France
  • Universität des Saarlandes, Germany
  • University Medical Center, Germany
  • University of Patras, Greece
  • University of Ioannina, Greece
  • University of Debrecen, Hungary
  • TDublin City University, Ireland
  • Weizmann Institute of Science, Israel
  • IRCCS AOU San Martino - IST National Cancer Research Institute, Italy
  • University of Ferrara, Italy
  • Rīga Stradiņš University, Latvia
  • University of Luxembourg, Luxembourg
  • Goce Delcev University, School of Medicine, North Macedonia
  • University of Bergen, Norway
  • Warsaw University of Life Sciences, Poland
  • International Institute of Molecular and Cell Biology, Poland
  • University of Minho, Portugal
  • University of Lisbon, Portugal
  • Institute for Oncology and Radiology of Serbia, Serbia
  • University of Belgrade, Serbia
  • University of Ljubljana, Slovenia
  • National Institute of Chemistry, Slovenia
  • Biomedical Research Institute of Murcia (IMIB-Arrixaca), Spain
  • CSIC, Spain
  • University of Geneva, Switzerland
  • Bilkent University, Turkey
  • Akdeniz University, Turkey
  • University of Sussex, United Kingdom
  • Medical University of Graz, Austria
  • Institute of Microbiology, ASCR, v.v i., Czech Republic
  • Glostrup Hospital, Denmark
  • University Medical Center Hamburg-Eppendorf, Germany
  • National Research Council (CNR), Italy
  • Istituto di Neuroscienze, Italy
  • University of Leicester, United Kingdom