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BIOLOGICAL SCIENCES IN RADIOLOGY

Academic year and teacher
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Versione italiana
Academic year
2022/2023
Teacher
CORRADO CITTANTI
Credits
3
Didactic period
Primo Semestre

Training objectives

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Modulo: 53321 - BIOLOGIA
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APPLIED BIOLOGY
Know the main functions of the cell and the mechanisms related to the preservation, expression and transmission of genetic information. Know the different biology approaches and techniques applied to diagnostic and scientific laboratories.

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Modulo: 53322 - RADIOBIOLOGIA
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Introduce basic principles and primary effects of interactions between ionizing radiations and biological structures.

Prerequisites

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Modulo: 53321 - BIOLOGIA (mutua dall'attività formativa BIOLOGIA APPLICATA AGLI STUDI BIOMEDICI - 53064 del CdS IGIENE DENTALE (abilitante alla professione sanitaria di Igienista dentale) - 1054)
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Basic biology.

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Modulo: 53322 - RADIOBIOLOGIA
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Basic biology and physics.

Course programme

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Modulo: 53321 - BIOLOGIA (mutua dall'attività formativa BIOLOGIA APPLICATA AGLI STUDI BIOMEDICI - 53064 del CdS IGIENE DENTALE (abilitante alla professione sanitaria di Igienista dentale) - 1054)
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BIOLOGY
Biological molecules: carbohydrates, lipids, proteins and nucleic acids
Prokaryotic cells, Eukaryotic cells: organelles. Biological membranes
Cell cycle, mitosis and meiosis. Structure and DNA replication. Genome organization
Transcription and translation. Laboratory techniques of cellular and molecular biology
Transport of membrane. Virus. Cell signaling

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Modulo: 53322 - RADIOBIOLOGIA
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Basic concepts in radiobiology. Electromagnetic radiations: spectrum and differential characteristics. "Natural" and "artificial" ionizing radiations and the ionization phenomenon. Interactions between radiations and living matter. "Direct" and "indirect" effects of ionizing radiations. Oxygen effect.
Cell cycle and its relationships with radiation exposure. Chromosomic and genic damage. Effects on cellular populations: "in vitro" cells' cultivation and "tumor dose 50". Dose-effect relation. Deterministic and stochastic effects of ionizing radiations.

Didactic methods

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Modulo: 53321 - BIOLOGIA (mutua dall'attività formativa BIOLOGIA APPLICATA AGLI STUDI BIOMEDICI - 53064 del CdS IGIENE DENTALE (abilitante alla professione sanitaria di Igienista dentale) - 1054)
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BIOLOGY
The teaching will take place through lectures conducted by the teacher with the use of support materials (slides) that will be made available on the course minisite.

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Modulo: 53322 - RADIOBIOLOGIA
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The teaching will take place through lectures conducted by the teacher with the use of support materials (slides) that will be made available on the course minisite. Lessons will be carried out online or in presence on the basis of the indications and guidelines of the University.

Learning assessment procedures

BIOLOGY
The oral or written exams will be conducted online or in presence according to the University's indications and guidelines. The test includes a written test consisting of 31 questions, some of which with a closed answer and some open-ended. For each correct answer 1 point. Verification with 31 positive responses on / 31 total, provides a score of 30/30 and laud. The written test lasts 45 minutes. The oral exam will consist of 3 open questions on the topics presented in class.
RADIOBIOLOGY
Oral exam: two random questions on various topics presented in the lectures (lasting 20-30 minutes) assessing clarity of presentation, reasoning ability and communication quality.
THE FINAL SCORE IS DERIVED FROM THE WEIGHTED AVERAGE OF THE TWO SEPARATE EVALUATIONS.

Reference texts

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Modulo: 53321 - BIOLOGIA (mutua dall'attività formativa BIOLOGIA APPLICATA AGLI STUDI BIOMEDICI - 53064 del CdS IGIENE DENTALE (abilitante alla professione sanitaria di Igienista dentale) - 1054)
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BIOLOGY
-De Leo, Fasano, Ginelli, Biologia e Genetica, Edizione EdiSE
-Solomom, Berg, Martin, Elementi di Biologia, Edizione EdiSES-Stefani e Taddei, Chimica Biochimica e Biologia Applicata, Ed. Zanichelli

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Modulo: 53322 - RADIOBIOLOGIA
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BIOLOGY
Teacher's handouts accompanied by textbook: Martinenghi C., Fossati V., Radiobiologia, Ed. Raffaello Cortina, Milano