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PHYSIOLOGY I

Academic year and teacher
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Versione italiana
Academic year
2022/2023
Teacher
LUCIANO FADIGA
Credits
9
Didactic period
Secondo Semestre
SSD
BIO/09

Training objectives

The aim of the course is to enable students to understand living processes in the human organism, providing the basis for the scientific understanding of pathological changes.
As for the parameters of:
Knowledge:
At the end of the course the student will:
- know the principles of cell biophysics;
- know the principles of the cardiovascular system;
- know the principles of the respiratory system;
- know the principles of the renal system;
- acquire the appropriate physiological terminology as well as knowledge about the essential parameters to evaluate the function of the systems.
Know-how:
At the end of the course the student will be able to:
- integrate knowledge about Physics, Biochemistry and Human Anatomy in a more general framework about the cell biophysics and the function of the cardiovascular, respiratory and renal system;
- the student at the end of the course will have acquired the tools required to evaluate pathology starting from basic physiological processes.

Prerequisites

Basic knowledge of the first principles of Physics, chemistry and biochemistry. Basic knowledge of human anatomy.
Passing exams of: Medical Physics and mathematics, Human anatomy II and propedeutical clinic, Biochemistry and Molecular Biology.

Course programme

Properties of excitable membranes. The resting potential. The action potential. The synaptic transmission. Contractility with special reference to the skeletal muscle. Muscle mechanics. Blood and lymph. The cardiovascular system: the heart as a pump; electrophysiology of the heart; circulatory mechanics; determinants and distribution of systemic blood flow; determinants of arterial blood pressure; control of the cardiovascular system; the microcirculation. Respiration: pulmonary mechanics; lung volumes and capacities; gas exchanges and transportation; the chemical regulation of ventilation. Nervous control of the breath. The kidney and body fluids: the glomerular filtration process; tubular transport processes, renal circulation; regulatory functions of the kidney; physiology of body fluids.

Didactic methods

The course provides frontal lectures and online assisted teaching. The on-line teaching hours of moodle platform certification service consist in the deepening of some topics presented during the frontal lessons.

Learning assessment procedures

The learning assessment will be conducted by means of a 60-minute written examination. The examination consists of 90 questions relating to all the learning objectives, with true/false answers. Each correct answer will be weighted according to the difficulty of the question, missing answers will be awarded 0 points, and each wrong answer will lead to a penalty. The minimum mark for passing the examination, 18/30, is achieved by acquiring 54 points.
The written test may be supplemented by an oral examination lasting a maximum of thirty minutes, at the student's request or at the teacher's suggestion for assessments close to the threshold.

Reference texts

Berne & Levy, Fisiologia, VI ed. a cura di B.M. Koeppen e B.A. Stanton - Casa Editrice Ambrosiana, Milano
E.R. Kandel, J.H. Schwartz, T.M. Jessell, S.A Siegelbaum, A.J. Hudspeth, Principi di neuroscienze, IV ed. - Casa Editrice Ambrosiana