PHARMACOLOGY AND PHARMACOTHERAPY II
Academic year and teacher
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- LUCA FERRARO
- Credits
- 9
- Didactic period
- Primo Semestre
- SSD
- BIO/14
Training objectives
- To develop knowledge and understanding of pharmacological and therapeutic properties of some classes of drugs.
To provide students with an integrated understanding of the characteristics and properties of drug molecules and how they interact with macromolecular drug targets in the body and other molecular components of medicines.
To build on physiological principles to develop students' understanding of pathophysiological mechanisms and systematic pharmacology. The students will learn about the underlying pathophysiology of some human diseases, and how the use of medicines can halt, slow the progression of, or reverse those disease processes. Prerequisites
- The following knowledges, acquired in “General and Inorganic Chemistry”, “Organic Chemistry”, “General and Applied Biochemistry”, “General Physiology”, “General Pathologies” and “Pharmacology and Pharmacotherapy I” modules, are required:
1) basic concepts of general and organic chemistry;
2) basic concepts of biochemistry;
3) fundamental concepts of physiology;
4) basic concepts of pathology.
To take the final examination (learning assessment procedures), students must have passed the exam of “Pharmacology and Pharmacotherapy I”. Course programme
- Formal teaching will consist of lectures (72 hours). The syllabus content is as follows:
Drugs active on the central nervous system: sedative-hypnotic drugs; antidepressant drugs; anti-psychosis drugs; antiepileptic drugs; drugs used in Parkinson's and Alzheimer's disease. Opioids and pain therapy.
Medicines for migraine / headache
Endocrine pharmacology: drugs used in hyper- and hypo-thyroidism; insulin, hypoglycemic agents and diabetes therapy; estrogens and progestogens; Bone homeostasis: drugs used in osteoporosis therapy.
Infectious disease therapy: 1) antibacterial drugs (Beta-lactam antibiotics; Aminiglycosides; Sulfonamides; Quinolones; Aminoglycosides; Tetracyclines; Macroclides and ketolides; Lincosamides). 2) Chemotherapy of malaria. 3) Antifungal drugs; 4) Antiviral drugs: anti-herpes virus, anti-flu, anti HBV, anti-HCV, HIV treatment (notes). Didactic methods
- Formal teaching consists of lectures and workshop-based integrated problem-solving exercises (live-streaming teaching due to COVID-19 pandemia.
Learning assessment procedures
- The level of achievement of previously indicated learning objectives is assessed through an oral exam. In particular, the exam aims to evaluate the study of the matter and the understanding of the main topics of pharmacology and pharmacotherapy.
The student must demonstrate the capacity to understand and discuss a leaflet or a monograph of a drug
In order to pass the exam, the student must obtain a minimum score of 18 out of 30. Reference texts
- 1) Basic and Clinical Pharmacology – Authors: B.G. Katzung, S.B. Masters, A.J. Trevor – Piccin Ed. (Italy).
2) Farmacologia - Autori: Rossi, Cuomo, Riccardi. Minerva medica Ed.
3) Goodman & Gilman: The Pharmacological Basis of Therapeutics. Zanichelli Ed. (Italy)
Lecture’ slides.
