PATHOLOGICAL ANATOMY II
Academic year and teacher
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- GIOVANNI LANZA
- Credits
- 5
- Didactic period
- Primo Semestre
- SSD
- MED/08
Training objectives
- The Pathology II course provides the systematic treatment of the pathological basis of diseases of the cardiovascular system, of the female genital tract, of the breast, of the central and peripheral nervous system, of the eye and of the head and neck.
Knowledge and understanding:
At the end of the course the student will:
- know the basic concepts about the epidemiological, etiopathogenetic, morphological, clinicopathological and biomolecular characteristics of pathological processes of the cardiovascular system, of the female genital tract, of the breast, of the central and peripheral nervous system, of the eye and of the head and neck.
- will be able to understand the clinical pictures related to different pathologies of the aforementioned systems and to understand pathology reports.
- know the biomolecular tests to be performed for target therapies and for immunotherapy in the main types of tumors.
- be aware of gender differences in incidence, diagnosis and treatment of various pathologies of the aforementioned systems.
Applying knowledge and understanding:
At the end of the course the student will have ability:
- to use the pathological information provided by morphology, immunohistochemistry and molecular biology, understanding their value in diagnosis, prognosis and therapy. Prerequisites
- Adequate knowledge of anatomy and histology of the cardiovascular system, of the female genital tract, of the breast, of the central and peripheral nervous system, of the eye and of the head and neck.
Knowledge of general pathology, genetics and molecular biology. Course programme
- Cardiovascular system: Heart: Ischemic heart disease, myocardial infarction. Cardiac hypertrophy. Myocarditis, endocarditis and pericarditis. Atherosclerosis, aneurysms.
Female genital tract: Vulva: Dystrophy. Vulvar intraepithelial neoplasia. Carcinoma.
Cervix: Cervical intraepithelial neoplasia. Squamous cell carcinoma. Cervical adenocarcinoma.
Endometrium: Endometriosis. Endometrial hyperplasia and adenocarcinoma. Stromal tumors
Tumors of the myometrium: Leiomyoma, leiomyosarcoma.
Ovarian tumors: Tumors of surface epithelium; germ cell tumors, gonadal and sex cord-stromal tumors.
Coriocarcinoma.
Breast: Benign lesions. Fibroepithelial tumors. In situ and invasive carcinoma. Nipple carcinoma.
Gynecomastia. Male breast carcinoma.
Central nervous system: Meningitis. Epidural and subdural hematoma. Intracerebral and subarachnoid hemorrhage. Ischemia and infarction.
Neurodegenerative diseases: Alzheimer's disease. Parkinson's disease
Glial and neuronal neoplasms. Embryonic tumors. Meningiomas. Metastatic tumors.
Peripheral nervous system: Peripheral neuropathies. Tumors
Pathology of the eye: Retinoblastoma. Melanoma
Head and neck: Oral cavity: Inflammatory-reactive lesions. Leukoplakia and erythroplakia. Squamous cell carcinoma. Odontogenic tumors and cysts: classification.
Nasopharynx, nasal cavity and paranasal sinuses: Tumors of the nasal / paranasal cavities.
Larynx: Polyps and papillomas. Carcinoma.
Salivary glands: Sialadenitis. Benign and malignant tumors. Didactic methods
- The Pathology II course provides frontal lectures and on-line assisted teaching. The on-line teaching on moodle platform certification service consists in deepening of some topics presented during the frontal lessons providing, in addition to the teaching material presented during lessons, clinical cases, guidelines and recommendations of scientific societies, scientific articles and learning assessment multiple choice test.
The teaching activity is also integrated by practical activity which consists in microscopic observation of histologic slides with routine and histochemical or immunohistochemical stains and exam and discussion of cases subjected to biomolecular analyses for diagnostic and prognostic-predictive purpose. Learning assessment procedures
- The learning verification will be carried out by a written exam consisting in 32 questions for a total duration of 30 minutes. The questions will be formulated with multiple choice questions (5 options for each question) relating to all the educational objectives of the course.
Each correct answer will be evaluated 1 point and there will be no penalty for incorrect or non-given answers. The exam mark is assigned in a scale out of thirty: 18/30 is the minimum for passing the exam, achieved by correctly answering to 18 questions, while the maximum mark, 30 cum laude, will be attributed to those who pass the score of 30. Reference texts
- Rubin, Anatomia patologica e Patologia Generale, Piccin Editore
Robbins e Cotran, Le basi patologiche delle malattie, Elsevier Editore
