PHARMACOLOGY
Academic year and teacher
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- Versione italiana
- Academic year
- 2018/2019
- Teacher
- MICHELE SIMONATO
- Credits
- 9
- Didactic period
- Secondo Semestre
- SSD
- BIO/14
Training objectives
- This course aims at providing the pharmacological basis of therapy, by explaining the mechanisms of drug action and how different drugs should be employed in the clinical settings. The course puts pharmacology in relation with other basic sciences, like physiology and biochemistry, and clinical sciences, with the goal of helping future doctors to plan correct pharmacological therapies. Finally, the course will illustrate gender-related differences in drug response due to pharmaco-dynamic and pharmaco-kinetic differences between sexes, to understand its influence in terms of pharmacological response and risk / benefit ratio of different drugs.
Prerequisites
- Knowledge of chemistry, biochemistry, physiology, anatomy, pathology.
Course programme
- Pharmacokinetics.
Drug absorption, distribution, metabolism, and elimination. Routes of drug administration.
Pharmacodynamics.
Mechanisms of drug action.
Gender-related differences in drug response.
Neurotransmission: the autonomic and somatic nervous systems.
Neurotransmission and the central nervous system.
Neuropharmacology: Antiepileptic drugs. General and local anesthetics. Anxiolytic and hypnotic drugs. Antidepressants. Antipsychotics. Anti-Parkinson and anti-Alzheimer drugs. Opioids.
Anti-inflammatory agents: Non-steroidal and steroidal anti-inflammatory drugs.
Anti-asthmatic agents.
Cardiovascular system drugs: Diuretics.
Antihypertensive drugs. Antianginal drugs. Anti-arrhythmic drugs. Drug therapy for hypercholesterolemia and dyslipidemia.
Pharmacotherapy of diabetes: insulin, oral hypoglycemic agents.
Drugs affecting gastrointestinal function: Antacids. Antiulcer drugs. Antiemetic Drugs.
Drug Addiction. Didactic methods
- Lectures
Learning assessment procedures
- The exam is divided into three parts:
(1) a written examination with open questions of Pharmacology, which aims to test the basic knowledge required for understanding the mode of action of drugs (pharmaco-kinetic and pharmaco dynamic)
(2) a multiple-choice tests on the entire Pharmacology Special, which has the purpose to verify the level of learning the subject matter
(3) an oral exam on Special Pharmacology, oriented to the verification of the ability to use the knowledge gained in clinical practice.
The three parts have a sequential order, whereby the exceeding of the first gives access to the second and that of the second gives access to the third.
The final vote will be the result of the weighted average of the rating of Pharmacology and combined the two tests of Special Pharmacology: at the General will be given a weight of 1 to the Special weighs 6. Reference texts
- Goodman and Gilman's, The Pharmacological Basis of Therapeutics, XII ed.
Katzung, Farmacologia Generale e Clinica
F. Rossi, V. Cuomo, C. Riccardi, Farmacologia. Principi di base e applicazioni terapeutiche, Edizioni Minerva Medica, Torino 2005
