ANATOMIC PATHOLOGY I
Academic year and teacher
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- Versione italiana
- Academic year
- 2018/2019
- Teacher
- GIOVANNI LANZA
- Credits
- 5
- Didactic period
- Secondo Semestre
- SSD
- MED/08
Training objectives
- After completing the course students learn the role of Pathology in modern clinical medicine and acquire knowledge about diagnostic applications of techniques currently in use including cytology, immunohistochemistry, and molecular biology applied to tissues. The course provides the systematic treatment of the pathological basis of diseases of the endocrine system, of the kidney and lower urinary tract, of the male genital system, of the respiratory system, of the gastrointestinal tract, of the liver, pancreas and biliary tract, of the skin, and of the hemolymphopoietic system. The student will know the basic concepts about etiology and morphological characteristics related to pathology of such organs. He will be able to understand the clinical pictures related to different pathologies and will be able to understand the pathology reports.
Prerequisites
- Adequate knowledge of anatomy of endocrine glands, of the urinary tract, of the male genital system, of the respiratory system, of the gastrointestinal tract, of liver, pancreas and biliary tract, of the skin and of the hemolymphopoietic system.
Knowledge of general pathology, genetics and molecular biology. Course programme
- Endocrine system: pituitary adenomas, thyroiditis, goiter, adenomas and carcinomas of the thyroid, hyperparathyroidism, hyperadrenalism, adrenocortical insufficiency, adrenocortical tumors, pheochromocytoma. MEN syndromes,
Urinary system:
kidney: inflammatory and vascular diseases, benign and malignant tumors of the kidney, renal metastases.
urinary tract: urolithiasis, cystitis, precancerous lesions and neoplasms of the urinary tract.
Male genital tract:
prostate: prostatitis, prostatic hyperplasia, prostatic carcinoma.
testis: germ cell tumors, tumors of sex cord-gonadal stroma.
Respiratory system:
lung: diffuse alveolar damage; pulmonary edema, pulmonary embolism, hemorrhage and infarction, obstructive pulmonary disease, bronchopneumonia, acute and chronic pneumonia, tuberculosis, sarcoidosis, chronic diffuse interstitial diseases; pneumoconioses, lung tumors, pulmonary metastatic tumors.
pleura: pleuritis, pleural tumors.
Gastrointestinal tract:
Esophagus: esophagitis, Barrett esophagus, esophageal tumors.
Stomach: gastritis, peptic ulcer disease, benign and malignant neoplasms
Small intestines and colon: malabsorption, intestinal obstruction, ischemic bowel disease, Crohn's disease, ulcerative colitis, diverticulosis and diverticulitis, polyps, malignant neoplasms
Appendix: appendicitis, tumors
Peritoneum: peritonitis, peritoneal tumors
Liver and biliary tract: acute and chronic infectious hepatitis, autoimmune hepatitis, metabolic fatty liver disease, liver cirrhosis, portal hypertension, benign and malignant tumors of the liver. Metastatic tumors.
Gallbladder disease: cholelithiasis, cholesterolosis, cholecystitis, benign and malignant tumors.
Pathology of the intra-hepatic biliary tract: secondary biliary cirrhosis, primary biliary cirrhosis, primary sclerosing cholangitis;
Pathology of the extrahepatic bile ducts: cholangitis.
Pancreas: acute and chronic pancreatitis, diabetes mellitus. Pancreatic carcinoma. Pancreatic neuroendocrine tumors.
Skin: non melanocytic lesions: actinic keratosis, squamous cell carcinoma, basal cell carcinoma.
melanocytic lesions: nevi and melanomas.
cutaneous lymphomas: mycosis fungoides.
Dermal lesions: benign fibroistiocitoma, DFSP.
Disease of the hemolymphopoietic system: Myeloid neoplasms: myeloproliferative neoplasms, myelodysplastic syndromes and acute leukemia
Lymphadenitis.
Lymphoid neoplasms: precursor B and T–cell neoplasms, peripheral B and T/NK cell neoplasms. Hodgkin lymphoma. Plasma cell dyscrasias.
Splenomegaly Didactic methods
- Lectures
Learning assessment procedures
- Oral examination: it consists on an average of two or three questions on various topics, lasting 30-40 min.
To evaluate the answers will be assessed the relevancy to the question, control of the topic and completeness of the information. Reference texts
- Robbins e Cotran, Le basi patologiche delle malattie, 8a ed. Elsevier
Rubin, Anatomia patologica, Piccin Nuova Libraria, 2014
Mariuzzi G.M., Anatomia patologica e correlazioni anatomo-cliniche, Piccin Nuova Libraria, 2006
