Paolo Pinton Lab__Signal Transduction

by BOTTONI ANDREA — last modified 03 Feb, 2012 09:47 PM

 

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  1. Rizzuto R, Pinton P, Carrington W, Fay FS, Fogarty KE, Lifshitz LM, Tuft RA, Pozzan T (1998) Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Science 280:1763-6 Download
  2. Pinton P, Pozzan T, Rizzuto R (1998) The Golgi apparatus is an inositol 1,4,5-trisphosphate-sensitive Ca2+ store, with functional properties distinct from those of the endoplasmic reticulum. EMBO J 17:5298-308 Download
  3. Pinton P, Brini M, Bastianutto C, Tuft RA, Pozzan T, Rizzuto R (1998) New light on mitochondrial calcium. Biofactors 8:243-53 Download
  4. De Giorgi F, Ahmed Z, Bastianutto C, Brini M, Jouaville LS, Marsault R, Murgia M, Pinton P, Pozzan T, Rizzuto R (1999) Targeting GFP to organelles.  Methods Cell Biol 58:75-85 Download
  5. Brini M, Pinton P, King MP, Davidson M, Schon EA, Rizzuto R (1999) A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency. Nature Medicine 5:951-54 Download
  6. Brini M, Pinton P, Pozzan T, Rizzuto R (1999) Targeted recombinant aequorins: tools for monitoring [Ca2+] in the various compartments of a living cell. Microsc Res Tech 46:380-9 Download
  7. Jouaville LS, Pinton P, Bastianutto C, Rutter GA, Rizzuto R (1999) Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming. Proc Natl Acad Sci USA 96:13807-12 Download
  8. Rizzuto R, Pinton P, Brini M, Chiesa A, Filippin L, Pozzan T (1999) Mitochondria as biosensors of calcium microdomains. Cell Calcium 26:193-9 Download
  9. Pinton P, Ferrari D, Magalhaes P, Schulze-Osthoff K, Di Virgilio F, Pozzan T, Rizzuto R (2000) Reduced loading of intracellular Ca2+ stores and downregulation of capacitative Ca2+ influx in Bcl-2-overexpressing cells. J Cell Biol 148:857-62 Download
  10. Robert V, Pinton P, Tosello V, Rizzuto R, Pozzan T (2000) Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments. Methods Enzymol 327:440-56 Download
  11. Chiesa A, Rapizzi E, Tosello V, Pinton P, de Virgilio M, Fogarty KE, Rizzuto R (2001) Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling. Biochem J 355:1-12 Download
  12. Porcelli AM, Pinton P, Ainscow EK, Chiesa A, Rugolo M, Rutter GA, Rizzuto R (2001) Targeting of reporter molecules to mitochondria to measure calcium, ATP, and pH. Methods Cell Biol 65:353-80 Download
  13. Pinton P, Ferrari D, Rapizzi E, Di Virgilio FD, Pozzan T, Rizzuto R (2001) The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J 20:2690-701 Download
  14. Chami M, Gozuacik D, Lagorce D, Brini M, Falson P, Peaucellier G, Pinton P, Lecoeur H, Gougeon ML, le Maire M, Rizzuto R, Brechot C, Paterlini-Brechot P (2001) SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis. J Cell Biol 153:1301-14 Download
  15. Mitchell KJ, Pinton P, Varadi A, Tacchetti C, Ainscow EK, Pozzan T, Rizzuto R, Rutter GA (2001) Dense core secretory vesicles revealed as a dynamic Ca2+ store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera. J Cell Biol 155:41-52 Download
  16. Pinton P, Ferrari D, Di Virgilio F, Pozzan T, Rizzuto R (2001) Molecular machinery and signaling events in apoptosis. Drug Dev Res 52: 558-70 Download
  17. Pinton P, Ferrari D, Rapizzi E, Di Virgilio F, Pozzan T, Rizzuto R (2002) A role for calcium in Bcl-2 action? Biochimie 84:195-201 Download
  18. Piccioni F, Pinton P, Simeoni S, Pozzi P, Fascio U, Vismara G, Martini L, Rizzuto R, Poletti A (2002) Androgen receptor with elongated polyglutamine tract forms aggregates that alter axonal trafficking and mitochondrial distribution in motor neuronal processes. FASEB J 16:1418-20 Download
  19. Pinton P, Tsuboi T, Ainscow EK, Pozzan T, Rizzuto R, Rutter GA (2002) Dynamics of Glucose-induced Membrane Recruitment of Protein Kinase C beta II in Living Pancreatic Islet beta -Cells. J Biol Chem 277:37702-10 Download
  20. Rapizzi E, Pinton P, Szabadkai G, Wieckowski MR, Vandecasteele G, Baird G, Tuft RA, Fogarty KE, Rizzuto R (2002) Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria. J Cell Biol 159:613-24 Download
  21. Ferrari D§, Pinton P§, Szabadkai G, Chami M, Campanella M, Pozzan T, Rizzuto R (2002) Endoplasmic reticulum, Bcl-2 and Ca2+ handling in apoptosis. Cell Calcium 32:413-20 §equally contributed Download
  22. Aguiari G, Campanella M, Manzati E, Pinton P, Banzi M, Moretti S, Rizzuto R, del Senno L. (2003) Expression of polycystin-1 C-terminal fragment enhances the ATP-induced Ca2+ release in human kidney cells. Biochem Biophys Res Commun 301:657-64 Download
  23. Morelli A, Chiozzi P, Chiesa A, Ferrari D, Sanz JM, Falzoni S, Pinton P, Rizzuto R, Olson MF, Di Virgilio F (2003) Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells. Mol Biol Cell 14:2655-6 Download
  24. Lasorsa FM, Pinton P, Palmieri L, Fiermonte G, Rizzuto R, Palmieri F (2003) Recombinant expression of the Ca2+-sensitive aspartate/glutamate carrier increases mitochondrial ATP production in agonist-stimulated CHO cells. J Biol Chem 278:38686-92 Download
  25. Rizzuto R, Pinton P, Ferrari D, Chami M, Szabadkai G, Magalhães PJ, Di Virgilio F, Pozzan T (2003) Calcium and apoptosis: facts and hypothesis. Oncogene 22:8619-27 Download
  26. Campanella M, De Jong AS, Lanke KW, Melchers WJ, Willems PH, Pinton P, Rizzuto R, van Kuppeveld FJ (2004) The coxsackievirus 2B protein suppresses apoptotic host cell responses by manipulating intracellular Ca2+ homeostasis. J Biol Chem 279:18440-50 Download
  27. Pinton P, Leo S, Wieckowski MR, Di Benedetto G, Rizzuto R (2004) Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes. J Cell Biol 165:223-32 Download
  28. Pinton P, Bianchi K, Prandini A, Rimessi A, Rizzuto R (2004) Ca2+ Homeostasis of Intracellular Compartments: measurements using the jellyfish photo-protein aequorin. Minerva Biotec 16:119-26 Download
  29. Tonachini L, Monticane M, Puri C, Tacchetti C, Pinton P, Rizzuto R, Cancedda R, Tavella S, Castagnola P (2004) Chondrocyte protein with a poly-proline region (CHPPR) is a novel mitochondrial protein and promotes mitochondrial fission. J Cell Physiol 201:470-82 Download
  30. Chami M, Prandini A, Campanella M, Pinton P, Szabadkai G, Reed JC, Rizzuto R (2004) Bcl-2 and Bax exert opposing effects on Ca2+ signalling, which do not depend on their putative pore-forming region. J Biol Chem 279:54581-89 Download
  31. Campanella M, Pinton P, Rizzuto R (2004) Mitochondrial Ca2+ homeostasis in health and disease. Biol Res 37:653-60 Download
  32. Porcelli AM, Ghelli M, Zanna C, Pinton P, Rizzuto R, Rugolo M. (2005) pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant. Biochem Biophys Res Commun 326:799-804 Download
  33. Biagioli M, Pinton P, Scudiero R, Ragghianti M, Bucci S, Rizzuto R (2005) Aequorin chimeras as valuable tool in the measurement of Ca2+ concentration during cadmium injury. Toxicology 208:389-98 Download
  34. Manzati E, Aguiari G, Banzi M, Manzati M, Selvatici R, Falzarano S, Maestri I, Pinton P, Rizzuto R , del Senno L (2005) The cytoplasmic C-terminus of polycystin-1 increases cell proliferation in kidney epithelial cells through serum-activated and Ca2+-dependent pathway(s). Exp Cell Res 304:391-406 Download
  35. Gallo A, Ceolotto G, Pinton P, Iori E, Murphy E, Rutter GA, Rizzuto R, Semplicini A, Avogaro A (2005) Metformin prevents glucose-induced PKC ß2 activation in Human Umbilical Vein Endothelial cells through an antioxidant mechanism. Diabetes 54:1123-3 Download
  36. Adinolfi E, Callegari MG, Ferrari D, Bolognesi C, Minelli M, Wieckowski MR, Pinton P, Rizzuto R, Di Virgilio F (2005) Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels and promotes serum-independent growth. Mol Biol Cell 16:3260-72 Download
  37. Pellegatti P, Falzoni S, Pinton P, Rizzuto R, Di Virgilio F (2005) A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. Mol Biol Cell 16:3659-65 Download
  38. Uccelletti D, Farina F, Pinton P, Goffrini P, Mancini P, Talora C, Rizzuto R, Palleschi C (2005) The Golgi Ca2+-ATPase KlPmr1p Function Is Required for Oxidative Stress Response by Controlling the Expression of the Heat Shock Element HSP60 in Kluyveromyces lactis. Mol Biol Cell 16:4636-47 Download
  39. Giorgio M, Migliaccio E, Orsini F, Paolucci D, Moroni M, Contursi C, Pelliccia G, Luzi L, Minucci S, Marcaccio M, Pinton P, Rizzuto R, Bernardi P, Paolucci P, Pelicci PG (2005) Electron transfer between cytochrome c and p66shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 122:221-33 Download
  40. Rimessi A, Coletto L, Pinton P, Rizzuto R, Brini M, Carafoli E (2005) Inhibitory interaction of protein 14-3-3ɛ with isoform 4 of the plasma membrane Ca2+ pump. J Biol Chem 280:37195-203 Download
  41. Pinotti M, Rizzotto L, Pinton P, Ferraresi P, Chuansumrit A, Charoenkwan P, Marchetti G, Rizzuto R, Mariani G, Bernardi F (2006) Intracellular readthrough of nonsense mutations by aminoglycosides in coagulation factor VII. Journal of Thrombosis and Haemostasis 4:1308-14 Download
  42. Pinton P, Rizzuto R (2006) Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum. Cell Death and Differentiation 13:1409-1418 Download
  43. Wieckowski MR, Szabadkai G, Wasilewski M, Pinton P, Duszyński J, Rizzuto R (2006) Overexpression of adenine nucleotide translocase reduces Ca2+ signal transmission between the ER and mitochondria. Biochem Biophys Res Commun 348:393-9 Download
  44. Banzi M, Aguiari G, Trimi V, Mangolini A, Pinton P, Witzgall R, Rizzuto R, del Senno L (2006) Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells. Biochem Biophys Res Commun 350:257-62 Download
  45. Rizzotto L, Pinotti M, Pinton P, Rizzuto R, Bernardi F (2006) Intracellular evaluation of ER targeting  elucidates a mild form of inherited coagulation deficiency. Molecular Medicine 12:137-42 Download
  46. Rapizzi E, Donati C, Cencetti F, Pinton P, Rizzuto R, Bruni P (2007) Sphingosine 1-phosphate receptors modulate intracellular Ca2+ homeostasis. Biochem Biophys Res Commun 353:268-74 Download
  47. Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, Contursi C, Minucci S, Mantovani F, Wieckowski MR, Del Sal G, Pelicci PG, Rizzuto R (2007) Protein Kinase C ß and Prolyl isomerase 1 regulate mitochondrial effects of the lifespan determinant p66Shc. Science 315:659-63 Download
  48. Pinton P, Rimessi A, Romagnoli A, Prandini A, Rizzuto R (2007) Biosensors for the detection of calcium and pH. Methods Cell Biol 80C:297-325 Download
  49. Romagnoli A, Aguiari P, De Stefani D, Leo S, Marchi S, Rimessi A, Zecchini E, Pinton P, Rizzuto R. (2007) The ER/mitochondria Ca2+ crosstalk Novartis Found Symp 287:122-31 Download
  50. Rimessi A, Rizzuto R, Pinton P (2007) Differential recruitment of PKC isoforms in HeLa cells during redox stress. Cell Stress & Chaperones 12:291-8 Download
  51. Zecchini E, Siviero R, Giorgi C, Rizzuto R, Pinton P (2007) Mitochondrial calcium signalling: message of life and death. Ital J Biochem 56:235-42 Download
  52. Biagioli M, Pifferi S, Ragghianti M, Bucci S, Rizzuto R, Pinton P (2008) Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis. Cell Calcium 43:184-95 Download
  53. Aguiari P, Leo, Zavan B, Vindigni V, Rimessi A, Bianchi K, Franzin C, Cortivo R, Rossato M, Vettor R, Abatangelo G, Pozzan T, Pinton P, Rizzuto R (2008) High glucose induces adipogenic differentiation of muscle-derived stem cells. Proc Natl Acad Sci USA 105:1226-31 Download
  54. Pinton P, Rizzuto R (2008) p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondria. Cell Cycle 7:304-8 Download
  55. Giorgi C, Romagnoli A, Pinton P, Rizzuto R (2008) Ca2+ signaling, mitochondria and cell death. Current Molecular Medicine 8:119-130 Download
  56. Lasorsa FM§, Pinton P§, Palmieri L, Scarcia P, Rottensteiner H, Rizzuto R, Palmieri F (2008) Peroxisomes as novel players in cell calcium homeostasis. J Biol Chem 283:15300-8 §equally contributed Download
  57. Aguiari G, Trimi V, Bogo M, Mangolini A, Szabadkai G, Pinton P, Witzgall R, Harris PC, Borea PA, Rizzuto R, del Senno L (2008) Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells. Cell Proliferation 41:554-573 Download
  58. Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, Criollo A, Morselli E, Zhu C, Harper F, Nannmark U, Samara C, Pinton P, Vicencio JM, Carnuccio R, Moll UM, Madeo F, Paterlini-Brechot P, Rizzuto R, Szabadkai G, Pierron G, Blomgren K, Tavernarakis N, Codogno P, Cecconi F, Kroemer G (2008) Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10:676-687 Download
  59. De Stefani D, Romagnoli A, Rizzuto R, Pinton P (2008) Gene silencing and mitochondrial signaling Minerva Biotec 20:89-98 Download
  60. Pinton P, Giorgi C, Siviero R, Zecchini E, Rizzuto R (2008) Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis. Oncogene 27:6407-18 Download
  61. Marchi S, Rimessi A, Giorgi C, Baldini C, Ferroni L, Rizzuto R, Pinton P (2008) Akt kinase reducing Endoplasmic Reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli. Biochem Biophys Res Commun 375:501-5 Download
  62. Rimessi A, Giorgi C, Pinton P*, Rizzuto R (2008) The versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death. Biochim Biophys Acta (Bioenergetics) 1777:808-16 *corresponding author Download
  63. Adinolfi E, Callegari MG, Cirillo M, Pinton P, Giorgi C, Cavagna D, Rizzuto R, Di Virgilio F (2009) Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis. J Biol Chem 284:10120-8 Download
  64. Celsi F, Pizzo P, Brini M, Leo S, Fotino C, Pinton P, Rizzuto R (2009) Mitochondria, calcium and cell death: a deadly triad in neurodegeneration. Biochim Biophys Acta (Bioenergetics) 1787:335-44 Download
  65. Murgia M, Giorgi C, Pinton P, Rizzuto R (2009) Controlling metabolism and cell death: at the heart of mitochondrial calcium signalling. J Mol Cell Cardiol 46:781-8 Download
  66. Lebiedzinska M, Duszynski J, Rizzuto R, Pinton P, Wieckowski MR (2009) Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues. Arch Biochem Biophys 486:73-80 Download
  67. Rizzuto R, Marchi S, Bonora M, Aguiari P, Bononi A, De Stefani D, Giorgi C, Leo S, Rimessi A, Siviero R, Zecchini E, Pinton P (2009) Ca(2+) transfer from the ER to mitochondria: when, how and why. Biochim Biophys Acta (Bioenergetics) 1787:1342-51 Download
  68. Giorgi C, De Stefani D, Bononi A, Rizzuto R, Pinton P (2009) Structural and functional link between the mitochondrial network and the endoplasmic reticulum. Int J Biochem Cell Biol 41:1817-27 Download
  69. Kozieł K, Lebiedzinska M, Szabadkai G, Onopiuk M, Brutkowski W, Wierzbicka K, Wilczyński G, Pinton P, Duszyński J, Zabłocki K, Wieckowski MR (2009) Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein is PAM involved in the capacitative calcium entry? Int J Biochem Cell Biol 41:2440-9 Download
  70. Rimessi A, Marchi S, Fotino C, Romagnoli A, Huebner K, Croce CM, Pinton P, Rizzuto R (2009) Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis. Proc Natl Acad Sci USA 106:12753-8 Download
  71. Wieckowski MR, Giorgi C, Lebiedzinska M, Duszynski J, Pinton P (2009) Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells. Nat Protoc 4:1582-90 Download
  72. Mangolini A, Bogo M, Durante C, Borgatti M, Gambari R, Harris PC, Rizzuto R, Pinton P, Aguiari G, Del Senno L (2010) NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells. Apoptosis 15:94-104 Download
  73. Ferrari D§, Pinton P§, Campanella M§, Callegari MG, Pizzirani C, Rimessi A, Di Virgilio F, Pozzan T, Rizzuto R (2010) Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C(2)-ceramide and CD95/APO-1/FAS receptor stimulation. Biochem Biophys Res Commun 391:575-81 §equally contributed Download
  74. Pavan C, Vindigni V, Michelotto L, Rimessi A, Abatangelo A, Cortivo R, Pinton P, Zavan B (2010) Weight gain related to treatment with atypical antipsychotics is due to activation of PKCß. Pharmacogenomics J 10(5):408-17 Download
  75. Giorgi C, Agnoletto C, Baldini C, Bononi A, Bonora M, Marchi S, Missiroli S, Patergnani S, Poletti F, Rimessi A, Zavan B, Pinton P (2010) Redox control of Protein Kinase C: cell and disease
 specific significances. Antioxid Redox Signal 13(7):1051-85 Download
  76. Biasiotto R, Aguiari P, Rizzuto R, Pinton P, D'Agostino DM, Criminale V (2010) The p13 protein of human T-cell leukemia virus type 1 (HTLV-1) modulates mitochondrial membrane potential and calcium uptake. Biochim Biophys Acta (Bioenergetics) 1797(6-7):945-951 Download
  77. Lebiedzinska M, Karkucinska-Wieckowska A, Giorgi C, Karczmarewicz E, Pronicka E, Pinton P, Duszynski P, Pronicki M, Wieckowski MR (2010) Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders. Biochim Biophys Acta (Bioenergetics) 1797(6-7):952-960 Download
  78. Cortivo R, Vindigni V, Iacobellis L, Abatangelo G, Pinton P, Zavan B (2010) Nanoscale particle therapies for wound and ulcers. Nanomedicine 5(4):641-56 Download
  79. Goitre L, Balzac F, Degani S, Degan P, Marchi S, Pinton P, Retta SF (2010) KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. Plos One 5(7):e11786 Download
  80. Giorgi C, Ito K, Lin H, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P*, Pandolfi PP (2010) PML regulates apoptosis at endoplasmic reticulum modulating calcium release. Science 330:1247-51 *corresponding author Download
  81. Demaria M, Giorgi C, Lebiedzinska M, Esposito G, D'Angeli L, Bartoli A, Gough DJ, Turkson J, Levy DE, Watson CJ, Wieckowski MR, Provero P, Pinton P, Poli V (2010) STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction. Aging 2(11):823-42 Download
  82. Bezzerri V, d'Adamo P, Rimessi A, Lanzara C, Crovella S, Nicolis E, Tamanini A, Athanasakis E, Tebon M, Bisoffi G, Drumm ML, Knowles MR, Pinton P*, Gasparini P*, Berton G*, Cabrini G* (2011) Phospholipase C-{beta}3 Is a Key Modulator of IL-8 Expression in Cystic Fibrosis Bronchial Epithelial Cells. J Immunol 186(8):4946-58 *share senior authorship Download
  83. Karkucinska-Wieckowska A, Lebiedzinska M, Jurkiewicz E, Pajdowska M, Trubicka J, Szymanska-Debinska T, Suski J, Pinton P, Duszynski J, Pronicki M, Wieckowski MR, Pronicka E (2011) Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria). Folia Neuropathol 49(1):56-63 Download
  84. Suski J, Lebiedzinska M, Machado NG, Oliveira PJ, Pinton P, Duszynski J,  Wieckowski MR (2011) Mitochondrial tolerance to drugs and toxic agents in ageing and disease. Current Drug Targets 12:827-849 Download
  85. Pinton P, Giorgi C, Pandolfi PP (2011) The role of PML in the control of apoptotic cell fate: a new key player at ER-mitochondria sites. Cell Death Differ 18(9):1450-6 Download
  86. Giorgi C, Wieckowski MR, Pandolfi PP, Pinton P (2011) Mitochondria associated membranes (MAMs) as critical hubs for apoptosis. Commun Integr Biol 4(3):334-5 Download
  87. Pinton P, Pavan C, Zavan B (2011) PKC-β activation and pharmacologically induced weight gain during antipsychotic treatment. Pharmacogenomics 12(4):453-5 Download
  88. Bertagnolo V, Nika E, Brugnoli F, Bonora M, Grassilli S, Pinton P, Capitani S (2011) Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells. Cell Tissue Res 345(1):163-75 Download
  89. Giorgi C, Romagnoli A, Agnoletto C, Bergamelli L, Sorrentino G, Brini M, Pozzan T, Meldolesi J, Pinton P*, Rizzuto R (2011) Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure. BMC Cell Biology 12:27 *corresponding author Download
  90. Suski JM, Karkucinska-Wieckowska A, Lebiedzinska M, Giorgi C, Szczepanowska J, Szabadkai G, Duszynski J, Pronicki M, Pinton P, Wieckowski MR (2011) p66Shc aging protein in control of fibroblasts cell fate. Int J Mol Sci 12(8):5373-89 Download
  91. Bononi A, Agnoletto C, De Marchi E, Marchi S, Patergnani S, Bonora M, Giorgi C, Missiroli S, Poletti F, Rimessi A, Pinton P (2011) Protein kinases and phosphatases in the control of cell fate. Enzyme Res 2011:329098 Download
  92. Patergnani S, Suski JM, Agnoletto C, Bononi A, Bonora M, De Marchi E, Giorgi C, Marchi S, Missiroli S, Poletti F, Rimessi A, Duszynski J, Wieckowski MR, Pinton P (2011) Calcium signaling around Mitochondria Associated Membranes (MAMs). Cell Commun Signal 9(1):19 Download
  93. Pesaresi MG, Amori I, Giorgi C, Ferri A, Fiorenzo P, Gabanella F, Salvatore AM, Giorgio M, Pelicci PG, Pinton P, Carri MT, Cozzolino M (2011) Mitochondrial redox signaling by p66Shc mediates ALS-like disease through Rac1 inactivation. Hum Mol Genet 20(21):4196-208 Download
  94. Gardin C, Vindigni V, Bressan E, Ferroni L, Nalesso E, Della Puppa A, D’Avella D, Lops D, Pinton P, Zavan B (2011) Hyaluronan and fibrin based scaffolds for the improvement of the neuronal differentiation of  adult stem cells derived from adipose tissue and skin. Int J Mol Sci 12(10):6749-64 Download
  95. Tombolan L, Orso F, Guzzardo V, Casara S, Zin A, Bonora M, Romualdi C, Giorgi C, Bisogno G, Alaggio R, Pinton P, De Pittà C, Taverna D, Rosolen A, Lanfranchi G (2011) High IGFBP2 expression correlates with tumor severity in pediatric rhabdomyosarcoma. Am J Pathol 179(5):2611-24 Download
  96. Gardin C, Bressan E, Ferroni L, Nalesso E, Vindigni V, Stellini E, Pinton P, Sivolella S, Zavan B (2011) In vitro concurrent endothelial and osteogenic commitment of adipose-derived stem cells and their genomical analyses through CGH array: novel strategies to increase the successful engraftment of a tissue engineered bone grafts. Stem Cells Dev [Epub ahead of print] Download
  97. Anelli T, Bergamelli L, Margittai E, Rimessi A, Fagioli C, Malgaroli A, Pinton P, Ripamonti M, Rizzuto R, Sitia R (2011) Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum-Mitochondria Interface (MAM). Antioxid Redox Signal [Epub ahead of print] Download
  98. De Stefani D, Bononi A, Romagnoli A, Messina A, De Pinto V, Pinton P, Rizzuto R (2012) VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria. Cell Death Differ 19:267-273 Download
  99. Suski J, Lebiedzinska M, Bonora M, Pinton P, Duszynski J, Wieckowski MR (2012) Relation between mitochondrial membrane potential and ROS formation. Methods in Molecular Biology 810:183-205 Download
  100. Marchi S, Giorgi C, Suski J, Agnoletto C, Bononi A, Bonora M, De Marchi E, Missiroli S, Patergnani S, Poletti F, Rimessi A, Duszynski J, Wieckowski MR, Pinton P (2012) Mitochondria-ROS crosstalk in the control of cell death and aging. J Signal Transduct 2012:329635 Download
  101. Giorgi C, Agnoletto C, Bononi A, Bonora M, De Marchi E, Marchi S, Missiroli S, Patergnani S, Poletti F, Rimessi A, Suski JM, Wieckowski MR, Pinton P (2012) Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion 12:77-85 Download
  102. Bononi A, Missiroli S, Poletti F, Suski JM, Agnoletto C, Bonora M, De Marchi E, Giorgi C, Marchi S, Patergnani S, Rimessi A, Wieckowski MR, Pinton P (2012) Mitochondria-associated membranes (MAMs) as hotspot Ca2+ signalling units. Adv Exp Med Biol In press
  103. Demaria M, Misale S, Giorgi C, Miano V, Campisi J, Pinton P, Poli V (2012) STAT3 can serve as a hit in the process of malignant transformation of primary cells. Cell Death Differ In press
  104. Rimessi A, Zecchini E, Siviero R, Giorgi C, Leo S, Rizzuto R, Pinton P (2012) The selective inhibition of nuclear PKCζ restores the effectiveness of chemotherapeutic agents in chemoresistant cells. Cell Cycle In press
  105. Garcia-Cao I, Song MS*, Hobbs RM*, Laurent G*, Giorgi C*, de Boer VC, Anastasiou D, Ito K, Sasaki A, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP (2012) Systemic super-elevation of PTEN induces an anti-Warburg tumor suppressive metabolic state. Cell In press *equally contributed
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